Product Description
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Terms of payment and delivery |
Production capacity |
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Payment terms: |
T/T,WU |
Production capacity: |
30 tons/year |
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min. Order: |
1 kg |
Package: |
according to customer requirements |
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Types of transport: |
Sea, air, land |
Delivery time: |
7 days |
Application
L-Serine
CAS: 56-45-1
EINECS: 200-274-3
Chem. formula: C3H7NO3
Appearance: White powder/crystals
!!! IMPORTANT FOR WORK!!!
- dissolves well in water
- is almost NOT soluble in alcohols -!!!
- melting point: ~220-228℃(decomposes)
- store in a dry place, tightly closed
BIOCHEMISTRY:
* essential amino acid (the body synthesizes it itself)
* participates in protein synthesis and cell division
* precursor of glycine and D-serine
* important for the formation of sphingolipids in the nervous system!!!
* synthesized in astrocytes via the phosphorylated pathway
NEUROPROTECTORY PROPERTIES:
- activates glycine receptors
- ↑ PPAR-y expression (important for microglial polarization!)
- anti-inflammatory. effect
- reduces neurotoxicity
- protects neurons from damage
CLINICAL STUDIES:
1) Inheritance. sensory neuropathy - 400 mg/kg/day - improvement!
2) Encephalopathy (GRIN2B mutations) - improvement in motor and cognitive functions
3) ALS (amyotrophic lateral sclerosis) - phase I - safe, phase II in progress
ADVANTAGES over D-serine:
- FDA approved for use!!!
- is not toxic to the kidneys
- crosses the BBB (blood-brain barrier) faster
- is safe for long periods of time. application
Our strengths
We can customize according to customer's requirements.
If you have any-questions, please write to us or call us.
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