What Is EDDHA Iron Chelate? The Ultimate Guide for High-pH Soils
Written by: ALEN, Chemical Engineer, MOSINTER | 15 years in "vitamin manufacturing" and "pharmaceutical APIs"

Last month, three procurement managers from major fruit plantations in South America asked me the same question: "Why does our iron sulfate fertilizer stop working as soon as the soil pH hits 7.5?" The answer lies in the chemical stability of the chelating agent. Standard iron sources precipitate into useless sludge in alkaline conditions, leaving your crops starving for nutrients.
EDDHA Iron Chelate (CAS 1170-02-1) is a specialized, high-stability fertilizer designed to remain 100% bioavailable even in extreme alkaline and calcareous soils (pH 4.0–9.0). Unlike EDTA, which fails above pH 6.5, EDDHA-Fe acts as a "molecular bodyguard," protecting iron ions from reacting with soil carbonates and ensuring they reach the plant roots effectively.
How Does EDDHA Iron Chelate Solve Iron Deficiency?
Are your crops showing "yellow leaf disease" (interveinal chlorosis) despite regular fertilization? This is a classic sign of iron lockout.
EDDHA-Fe solves this by using a unique ortho-ortho isomer structure that forms a stable hexadentate complex with ferric iron (Fe³⁺), preventing it from turning into insoluble iron hydroxide.
What most suppliers won't tell you is that not all EDDHA is created equal. The efficacy depends heavily on the "ortho-ortho" isomer content. At MOSINTER, our 21 years of experience in chemical engineering allow us to optimize this ratio, providing what researchers call the "iron shuttle effect"-where the chelate continuously picks up iron from the soil and delivers it to the root membrane.
|
Property |
Value/Detail |
|
CAS Number |
1170-02-1 |
|
Solubility |
100% Water Soluble |
|
Stability Range |
pH 4.0 – 9.0 (Up to 11.0 in some formulations) |
|
Appearance |
Dark Red to Black Microgranules/Powder |

Key Specifications and Technical Parameters
Why should a procurement officer care about the melting point or molecular formula? Because purity determines your ROI.
Our EDDHA Iron Chelate (Ethylenebis(o-hydroxyphenyl)glycine) features a high purity level with a molecular weight of 360.36, ensuring rapid absorption without leaving harmful residues in the soil.
As a chemical engineer, I've seen many "low-cost" alternatives that contain high levels of unreacted phenol or sodium salts, which can actually damage soil structure over time. According to PubChem (CID 14432), the molecular structure must be precise to maintain its "green" profile.
|
Technical Parameter |
Specification |
|
Molecular Formula |
C18H20N2O6 |
|
Density |
~1.3595 (Rough estimate) |
|
Boiling Point |
492.4°C (Rough estimate) |
|
Melting Point |
>215°C (Decomposition) |
EDDHA vs. EDTA: Which Should You Choose?
Are you wasting money on the wrong chelate? Most buyers choose EDTA because it's cheaper, but in alkaline soil, it's a total loss.
EDDHA-Fe is the "gold standard" for soils with pH > 7.5, while EDTA is better suited for acidic soils (pH < 6.5) or foliar applications where quick, temporary absorption is needed.
Scientific studies from institutions like ResearchGate show that EDDHA-Fe can increase crop yields by up to 30% in calcareous environments by maintaining iron in a soluble form that EDTA simply cannot protect.
|
Feature |
EDTA-Fe |
EDDHA-Fe |
|
Optimal pH Range |
4.0 – 6.5 |
4.0 – 9.0+ |
|
Soil Stability |
Short-lived in alkaline soil |
Long-lasting/Persistent |
|
Application |
Foliar Spray / Acidic Soil |
Soil Drench / Alkaline Soil |
|
Cost Efficiency |
Low (High loss in high pH) |
High (Maximum bioavailability) |
Application Guide for Fruit Trees and Vegetables
How do you apply it for maximum effect? Applying it at the wrong time or method can lead to leaching.
For best results, EDDHA-Fe should be applied directly to the soil via drenching or fertigation during the early spring growth flush, ensuring the chelate reaches the root zone before intense sunlight can degrade it.
|
Crop Type |
Recommended Dosage |
Method |
|
Large Fruit Trees |
50g – 200g per tree |
Soil drench at drip line |
|
Small Fruit Trees |
25g – 100g per tree |
Soil drench |
|
Vegetables |
2.5 – 5 lbs per acre |
Band or sidedress at planting |
|
Ornamentals/Shrubs |
2 oz per inch of trunk diameter |
Broadcast and irrigate |
For those in the cannabis cultivation or hydroponics sector, EDDHA is often the preferred choice when using hard water, as it prevents the iron lockout that frequently plagues these sensitive systems.

Frequently Asked Questions (FAQ)
1. Is EDDHA-Fe safe for the environment?
Yes. When used according to guidelines, it is a "green" product with no waste residue. While synthetic, its high efficiency reduces the need for repeated, high-volume applications of less stable fertilizers.
2. Can I mix EDDHA-Fe with other fertilizers?
Generally, yes. It is highly compatible with most water-soluble fertilizers and NPK blends. However, avoid mixing with concentrated oils or miticides unless tested first.
3. Why is the color of the product white to light brown in some specs but dark red in others?
The pure chelating agent EDDHA is white to light brown. Once it is chelated with iron (Fe), it turns into a characteristic dark red or blackish microgranule.
4. How long does the effect last in the soil?
Because of its high stability constant, one application of EDDHA-Fe can remain effective for a full growing season, unlike iron sulfate which may need monthly re-application.
5. Can it be used in hydroponics?
Absolutely. It is the best choice for hydroponic systems with fluctuating pH levels (above 6.5) to ensure iron remains available regardless of environmental changes.

Conclusion
EDDHA Iron Chelate is not just another fertilizer; it is a critical insurance policy for crops grown in challenging soil conditions. By choosing a high-purity product like MOSINTER's, you ensure maximum photosynthesis and yield while protecting your soil's long-term health.
Ready to boost your crop yield? Contact our engineering team for a customized nutrient plan.
WhatsApp: +8618989305995
Email: info1@mosinterchem.com
Website: View Product Details
Last Updated: January 2026


